Reconstruction of cysteine biosynthesis using engineered cysteine-free enzymes
نویسندگان
چکیده
منابع مشابه
Reconstruction of cysteine biosynthesis using engineered cysteine-free and methionine-free enzymes
Ten of the proteinogenic amino acids can be generated abiotically while the remaining thirteen require biology for their synthesis. Paradoxically, the biosynthesis pathways observed in nature require enzymes that are made with the amino acids they produce. For example, Escherichia coli produces cysteine from serine via two enzymes that contain cysteine. Here, we substituted alternate amino acid...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-19920-y